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Leibniz Graduate School (LGS) SynaptoGenetics

Cooperation

  • Leibniz Institute for Neurobiology (LIN)
  • Otto-von-Guericke-Universität Magdeburg (OVGU)

Objectives

The human brain is the most complex organ where about one hundred billion neurons and a similar number of glial cells form trillions of specialized cellular connections, the synapses. Synapses are dynamic structures, enabling the brain to establish various modes of performance, from simple regulatory activity to learning, memory and cognition. Recent developments in genetics and molecular biology allowed pivotal contributions to understanding synaptic function and dysfunctions (so-called synaptopathies), for instance by analyzing synaptic networks or by using distinct models for neuropathological diseases. Especially, sophisticated cell-specific genetic approaches in both the fruit fly Drosophila and the mouse enable the in-depth analysis of synaptic functions. In addition, modern human genetics in combination with next-generation sequencing techniques has revealed many potential disease-related genes. With this versatile toolbox the LGS on SynaptoGenetics aims at deciphering complex mechanisms of synaptic function and dysfunction.

Activities

  • Workshops/Courses
  • Soft Skill lecture series
  • Women in Science Days
  • Annual Retreat

Funding Organizations

Leibniz Association

Partners in the Network